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Make sure to check the FAQ before asking your questions !
First of all, click here to see our authorized 'Supplement Facts' label.
And then use Google to look for additional details on Maitake's therapeutic potential - you will read about the 'D-Fraction®*', the 'MD-Fraction' and others.
The d-fraction is originally a term coined in the 1980s; it referred then to a purified -fractionated- beta-glucan, bonded with a protein; a so-called 'proteoglycan'. This particular fraction showed a lot of promise because of its anti-tumor potential.
Unfortunately, neither this product nor its successor, the md-fraction (a more pure version of the d-fraction, patented in 1997) is for sale in its undiluted pure form; the production costs are probably too high (it's a 200 : 1 extract) and the fractionating process is too complex for mass-production.
Although the manufacturers prefer to keep the details as vague as possible (marketing reasons), here are some -verifiable- facts:
Summarizing: Based on the existing facts we feel confident ORIVeDA Grifolan® is at least equal to, if not more potent than the best of the current commercially available Maitake products. Apart from that, the value for money is much better.*D-Fraction® and PD-Fraction® are trademarks of Mushroom Wisdom, Inc., NJ, USA. MaitakeGold 404® (MTG) is a trademark of The Tradeworks Group, VT, USA
Maitake's therapeutic potential has been researched intensively since the late 1970s. It was the hype of the day during the 1990's, a reputation based on promising research results. Below is a list of the main targets of this research; due to legal restrictions we can't give more details. Take notice: this list should not be interpreted as a list of medical claims !
Our research section has several interesting publications, free to download.
Before you start using Google, read the other entry on this page: 'Why ORIVeDA's Grifolan ?' or, even better, read this extensive background article.
Because Maitake has immune-balancing properties, it should not be used together with immune-suppressants, like those prescribed after a transplant.
The blood sugar lowering effects can cause temporary fatigue in those that are highly susceptible. In general these people are also very susceptible to e.g. caffeine and alcohol, or are diabetics. Taking the extract together with a sugar containing liquid can neutralise this effect.
In general Maitake is safe to use, even in high doses and for extended periods of time.
Grifola frondosa, Maitake, Grifolan, immune support
Immunological effects of 39 mushroom supplements compared. [source]