Grifolan is the world's most potent Maitake extract

Each vegetarian capsule contains 390 mg fractionated Maitake extract.
120 capsules cover 2 months. (2 capsules daily)

  • • over 60 % polysaccharides ( > 65 % are bioactive (1>3)(1>6) Beta-D-Glucans)
  • • fractionated hot water extract: contains mostly high molecular weight beta-glucans and proteoglycans (≥ 150 mg per capsule)
  • (Click here for our supplement facts label with full specs and directions for use)
No additives or fillers, USDA-organic, GMO-free, non-irradiated. Premium product, 100 % purity. This product contains no non-extracted mushroom powder!
100 % hot water extracted Maitake powder(from cultivated fruiting bodies - organic)

ORIVeDA Grifolan supplement facts label

Which medicinal mushroom is the best?

Medicinal mushrooms seem like small miracles - their therapeutic properties seem to cover almost the full spectrum of human health and well-being. And this is not exaggerated. The majority of antibiotics, several chemo-therapeutic agents, most anti-cholesterol medication (statins) and some anti-HIV medication are based on fungi. Cyclosporin, a drug without which organ transplants would be impossible, is derived from a fungus as well. And so on.

In fact, most mushrooms have only been researched for a small number of therapeutic applications. The chart below gives an indication of the existing research results of the therapeutic properties that were investigated so far.

Please take notice: 'immune balancing' covers a lot of health problems, including many allergies and auto-immune related diseases. These have not been listed separately. This overview is also not complete - we will update it and refine it when more data becomes available.

Be aware of the fact that if a property is left blank for a particular mushroom this only means that this property so far has not been investigated in depth.

overview of positive results achieved with medicinal mushroom extracts as sold by ORIVeDA

These results have all been achieved with extracted mushroom products (extraction using e.g. hot water, ethanol, methanol, fermentation or combinations of these) - they are not applicable to biomass or un-extracted, dried and powdered mushroom products or tinctures. Check our FAQ for the reason why.

free shipping worldwide

We have customers in over 85 countries. We will ship to all countries in the world, except warzones. Orders will be shipped the same day they're received, if possible.

All website orders, national and international, are shipped for free using priority-airmail, which is safe and fast.

Only for Australia, Russia, Malaysia, Israel, Indonesia, India, all South- and Central-American countries and a few others registered shipping (which includes tracking) is mandatory. The postal service can be unpredictable in these countries and orders sometimes spend over a month in transfer, if not registered and tracked. Standard priority airmail does not include tracking !! You will see the available options when checking out.

We also provide express delivery (2 - 5 working days via FedEx) to 16 non-EU countries. The costs vary between $ 20 to $ 35 for orders up to 500 grams (4 items), depending on your location.

Shipments to EU countries usually arrive within 4 - 10 working days; international shipments usually arrive within 8 - 10 working days. Due to random custom clearance procedures non-EU orders can occasionally take up to 20 working days to arrive, but this is rare.
In case you haven't received your order after 20 working days please contact us and we will investigate. Do NOT open a Paypal case, but contact us directly.

Payment and security - click here..
Wholesale prices

You are eligible for a quantity discount when you order more than 10 items, mix 'n match. You can also buy capsules and powder in bulk (MOQ: 1 kilo).

Mumijo • Shilajit and Stone Oil are excluded.
Contact us for details and the price list.

Our affiliate program - click here

Why Maitake ?

Maitake's therapeutic potential has been researched intensively since the late 1970s. Below is a list of the main targets of this research***. Due to legal restrictions we can't give more details. Our research section has several interesting publications, free to download.

Before you start using Google, read the column next to this one: 'Why choose ORIVeDA's Grifolan ?' or, even better, read this extensive background article.

  • • Maitake's anti-viral and anti-tumor potential (in vivo, in vitro and clinical tests)

  • • Maitake's cardiovascular effects

  • • The effect on the Chronic fatigue syndrome (CFS)

  • • General balancing of the immune system. Maitake is considered 'King of Immunity'

  • • The effect on diabetes. Maitake contains a natural alpha glucosidase inhibitor, which lowers blood sugar

  • • Blood pressure regulation

  • • Anti-cancer adjuvant - using purified Maitake extracts together with regular treatment seemed to improve the effects considerably.

  • • Side effects, contraindications


Grifola frondosa, Maitake, anti-diabetic, anti-cancer adjuvant, anti-cholesterol, Grifolan, immune support, anti-viral, anti-cancer

Sign up for our newsletter    published 2 - 3 times per year.

Why choose ORIVeDA's Grifolan ?

When you use Google to look for additional details on Maitake's therapeutic potential you will read about the 'D-Fraction®*', the 'MD-Fraction' and others.

The d-fraction is originally a term coined in the 1980s; it referred then to a purified -fractionated- beta-glucan, bonded with a protein; a so-called 'proteoglycan'. This particular fraction showed a lot of promise because of its anti-tumor potential.

Unfortunately, neither this product nor its successor, the md-fraction (a more pure version of the d-fraction, patented in 1997) is for sale in its undiluted pure form; the production costs are too high (it's a 200 : 1 extract) and the fractionating process is too complex for mass-production.

Although the manufacturers prefer to keep the details as vague as possible (marketing reasons), here are some -verifiable- facts:

click for details...

  • Apart from being a research-term, 'D-Fraction®' is also a trademark*, registered in 1995. Products sold with the name 'D-Fraction®' contain, according to the label 'PD-Fraction®*' (which stands for 'Pre-D-Fraction'). It is unclear what this is.

  • The commercial 'D-Fraction®' has been tested against another Maitake extract, MaitakeGold 404®* (MTG), containing (according to that same test rapport and a follow-up) a diluted version of the md-fraction. The test involved many immunological parameters. MTG scored significantly better in all tests.

  • MTG is standardised for ≥ 20% (1>3)(1>6)beta-glucans (though not on the label; only in B2B communication). Nothing else.
    The glucan/protein ratio is not revealed, although this would be an easy and cheap way to authenticate the product as being pure (the ratio should be between ± 2 : 1 (= d-fraction purity) all the way to 99 : 1 (= md-fraction purity) according to the patents).

  • MTG is sold only in liquid form; 1 gram of extract dissolved in 30 ml of liquid. The recommended daily dosage is 8 - 16 drops daily, which equals 19 - 77 mg MTG.
    The optimal dosage of this extract is, according to independent research (a clinical trial), 7 mg/kg bodyweight/day (e.g. a 60 kg person should take ± 420mg daily), which is significantly more.

  • ORIVeDA's Grifolan is standarised for ≥ 40 % (1>3)(1>6)beta-glucans, has a glucan/protein ratio of 1.72 : 1 (close to the original d-fraction) and can deliver the recommended daily dosage for optimal immunological effect easily. Because the extract used in the research was more pure than any commercially available product, the dosage should be adjusted accordingly: we recommend at least 4 - 8 capsules per day (each with ≥ 150 mg beta-glucans) if maximum therapeutic potential is needed. (The standard dose for normal immune support is 2 capsules daily.)

Summarizing, based on the existing facts we feel confident ORIVeDA Grifolan® is at least equal to, if not more potent than the best of the current commercially available Maitake products. Apart from that, the value for money is much better.

Certified and produced in compliance with ISO 9001:2008, GMP, HACCP.

▲ hide details ▲

*D-Fraction® and PD-Fraction® are trademarks of Mushroom Wisdom, Inc., NJ, USA. MaitakeGold 404® (MTG) is a trademark of The Tradeworks Group, VT, USA
find out the positive results of research done with the mushrooms we sell
free shipping worldwide interesting quantity discounts and an interesting affiliate program

Quantity discounts available
Click here for info, includes info about our affiliate program.