top  picture
ORIVeDA Lion's Mane is the world's most potent Lion's Mane extract

S p e c ia l   o f f e r  :

every second item $ 6.99 off!

Each vegetarian capsule contains 300 mg pharmaceutical grade Lion's Mane extract.
180 caps will cover 2 months. (3 capsules daily)

  • • contains over 40 % polysaccharides ( with ≥ 38 % bioactive (1>3)(1>6) Beta-D-Glucans )

  • Click here to see the full supplement facts label
No additives or fillers, certified organic, GMO-free, non-irradiated.
This premium product is a 100% hot water extract of wood-grown Lion's Mane fruiting bodies and deep layer cultivated mycelium (50/50 ratio).

ORIVeDA Lion's Mane supplement facts label

Which medicinal mushroom is the best?

Medicinal mushrooms seem like small miracles - their therapeutic properties seem to cover almost the full spectrum of human health and well-being. And this is not exaggerated. The majority of antibiotics, several chemo-therapeutic agents, most anti-cholesterol medication (statins) and some anti-HIV medication are based on fungi. Cyclosporin, a drug without which organ transplants would be impossible, is derived from a fungus as well. And so on.

In fact, most mushrooms have only been researched for a small number of therapeutic applications. The chart below gives an indication of the existing research results of the therapeutic properties that were investigated so far.

Please take notice: 'immune balancing' covers a lot of health problems, including many allergies and auto-immune related diseases. These have not been listed separately. This overview is also not complete - we will update it and refine it when more data becomes available.

Be aware of the fact that if a property is left blank for a particular mushroom this only means that this property so far has not been investigated in depth.

overview of positive results achieved with medicinal mushroom extracts as sold by ORIVeDA

These results have all been achieved with extracted mushroom products (extraction using e.g. hot water, ethanol, methanol, fermentation or combinations of these) - they are not applicable to biomass or un-extracted, dried and powdered mushroom products or tinctures. Check our FAQ for the reason why.

free shipping worldwide

We have customers in over 85 countries. We will ship to all countries in the world, except warzones. Orders will be shipped the same day they're received, if possible.

All website orders, national and international, are shipped for free using priority-airmail, which is safe and fast.

Only for Australia, Russia, Malaysia, Israel, Indonesia, India, all South- and Central-American countries and a few others registered shipping (which includes tracking) is mandatory. The postal service can be unpredictable in these countries and orders sometimes spend over a month in transfer, if not registered and tracked. Standard priority airmail does not include tracking !! You will see the available options when checking out.

We also provide express delivery (2 - 5 working days via FedEx) to 16 non-EU countries. The costs vary between $ 20 to $ 35 for orders up to 500 grams (4 items), depending on your location.

Shipments to EU countries usually arrive within 4 - 10 working days; international shipments usually arrive within 8 - 10 working days. Due to random custom clearance procedures non-EU orders can occasionally take up to 20 working days to arrive, but this is rare.
In case you haven't received your order after 20 working days please contact us and we will investigate. Do NOT open a Paypal case, but contact us directly.

Payment and security - click here..
Wholesale prices

You are eligible for a quantity discount when you order more than 10 items, mix 'n match. You can also buy capsules and powder in bulk (MOQ: 1 kilo).

Mumijo • Shilajit and Stone Oil are excluded.
Contact us for details and the price list.

Our affiliate program - click here

Why choose Lion's Mane ?

Science has been researching medicinal mushrooms for decades. Below we've listed the main targets in Lion's Mane research***. A more detailed in-depth article can be found here (opens in a new window).
Take notice: this list should not be interpreted as a list of medical claims!

  • • Potential for Immunomodulation

    A shared property of all medicinal mushrooms is said to be immune-modulation: research has been investigating their potential to normalize our natural resistance against diseases for many decades. Although undeniable proof has not yet been presented the outcome of research is promising.

    In particular water-soluble beta-glucans triggered the interest of scientists: in the EU several health-claims based on beta-glucans have been ratified in the past years by the EFSA. Beta-glucans are e.g. thought to help with immune support and with normalizing of cholesterol levels.

    Given that our immune system is the core of our health this is a very important subject - allergies, infections, auto-immune diseases and many old-age problems are all immune-related.

    Two terms are read often in this context: adaptogenic (helping our body to adapt to the never-ending assaults on our health) and BRM (a natural Biological Response Modifier - helps to normalize the body's natural defense mechanisms without any side effects). These terms are keywords when describing medicinal mushrooms. Medicinal mushrooms do not cure or heal, but they support the body's own ability to stay healthy and perform at its best.

  • • Potential for Anti-Gastritis and Anti-Ulcer effects

    Traditionally Lion's Mane was used to treat peptic ulcers and chronic gastritis.

    Most people are carriers of the Helicobacter pylori bacteria in their stomach. This bacteria is mostly harmless until a compromised immune system allows it to cause inflammations, which in due time can lead to peptic ulcers. By helping the immune function Lion's Mane can help to prevent these ulcers, and its anti-inflammatory properties might help to cure them. This traditional usage has been tested in vivo and in vitro.

    Ulcers that are caused by damaged mucosal layers in the gastro-intestinal tract can also benefit from Lion's Mane.

    We quote from a recent research study: "The aqueous extract of H. erinaceus protected gastric mucosa against ethanol-induced injury. The protection was shown to be dose dependent [...] protection was significant at the maximum dosage at 400mg/kg."

    The full article can be read here.

  • • Potential Anti-Diabetic effects

    There are indications that mushroom extracts that are rich in beta-glucans can be benificial for diabetics.

    We quote from a recent research article (in vivo research): "[Administration of a Lion's Mane hot water extract for 28 days] resulted in a significant decrease in serum glucose level and a significant rise in serum insulin level. [The] treatment attenuated lipid disorders."

    The full article can be read here.

  • • Improving cognitive functions and stimulating the Nerve Growth Factor

    Nerve growth factor (NGF) is a secreted protein that is important for the growth, maintenance, survival and regeneration of nerve cells, and is considered critical for their survival. Without it, these nerve cells / neurons will die, causing both cognitive and motoric problems. The discovery of the NGF was in the 1950s, and the scientists responsible received the Nobel Prize in 1986 for this, when the importance of the NGF was finally aknowlegded. NGF prevents or reduces the degeneration of nerve cells such as caused by neurodegenerative diseases (e.g. Alzheimer's) and aging.

    Lion's Mane was found to contain a class of compounds that stimulate the production of NGF, indirectly stimulating nerves to regrow. These compounds, called Hericenones (found mainly in the fruiting body) and Erinacines (found mainly in the mycelium), are so far the only active substances found in natural products that can induce the production of the NGF. These bioactives therefore might have great potential for -indirectly- repairing neurological damage, improving intelligence (cognition) and reflexes and, even more significant, preventing and treating neurodegenerative diseases like Alzheimer's.

    We quote from a recent clinical trial (duration: 16 weeks) performed with 50- to 80-year-old Japanese men and women diagnosed with mild cognitive impairment: [...] At weeks 8, 12 and 16 of the trial, the [Lion's Mane] group showed significantly increased scores on the cognitive function scale compared with the placebo group. The [Lion's Mane] group's scores increased with the duration of intake.[...] The results obtained in this study suggest that [Lion's Mane] is effective in improving mild cognitive impairment."

    The full article can be read here.

  • • Potential effects on menopausal problems, depression, anxiety

    The NGF inducing bioactives in Lion's Mane also appear to work on other areas of the brain, including areas that are related to Rett syndrome and bipolar disorder. Menopausal problems also include a mental element. Stress and/or anxiety are usually a precipitating factor in all of these and might negatively affect the levels of NGF.

    We quote from a recent clinical trial (2010; duration: 4 weeks) performed with 30 women in the menopausal age: [...] "Concentration", "irritating" and "anxious" tended to be lower than the placebo group. Our results show that HE intake has the possibility to reduce depression and anxiety and these results suggest a different mechanism from NGF-enhancing action of H. erinaceus.[...]".

    The full article can be read here.

  • • Side effects, contra-indications

    There are no known side effects.

    However, just like with other medicinal mushrooms, because Lion's Mane has immune-balancing properties, it should not be used together with immune-suppressants, like those prescribed after a transplant.

    The blood sugar lowering effects can cause fatigue in those that are highly susceptible. In general these people are also very susceptible to e.g. caffeine and alcohol, or are diabetic. Taking the extract together with a sugar-containing liquid can neutralise this effect.

Hericium erinaceus, Lion's Mane, anti-diabetic, NGF (Nerve Growth Factor), immune support, anti-anxiety, anti-gastritis, anti-ulcer

Sign up for our newsletter    published 2 - 3 times per year.

Why choose ORIVeDA's Lion's Mane extract ?

ORIVeDA's Lion's Mane is a hot water extracted and highly purified product. It's the only Lion's Mane extract, worldwide, that contains pure -deep layer cultivated*- mycelium extract.

more details..

We guarantee the percentages of several bioactive compounds, optimal bioavailability and therapeutic effect.

Lion's Mane has been -and still is- the subject of intensive research, in particular after the NGF-stimulating compounds were discovered. Check this link (opens in a new window) for a more extensive explanation.

Scientific research is mainly using hot water extracts, usually followed by alcohol precipitation to further purify the extract.

ORIVeDA's Lion's Mane is identical to the extracts as used in research, but with a higher level of bioactives. This is due to a proprietary and patented extraction process with a very high yield (at least twice the level found in other LM extracts on the market).

Extraction is essential for therapeutic potency, since we cannot digest non-extracted mushrooms properly.
See this -highly recommended!- link for the details about this.

Dual extraction is usually the best option - but in the case of Lion's Mane this is unfortunately impossible, due to technical limitations. Luckily, the described therapeutic effects were all achieved with hot water extracts, so apparently dual extraction wouldn't add much.

Summarizing: The percentages of bioactives in ORIVeDA's Lion's Mane extract are -verifiable (!)- the best in the world and their bioavailability is 100%. Currently there is no product with better therapeutic properties and a better value for money available. (More details: see this blogpost)

Certified and produced in compliance with ISO 9001:2008, GMP, HACCP.

▲ hide details ▲

*deep layer cultivated = cultivated in liquid, instead of on grains or rice. The final product is 100% pure and free from leftover grains/rice (starch).
find out the positive results of research done with the mushrooms we sell
free shipping worldwide interesting quantity discounts and an interesting affiliate program

Quantity discounts available
Click here for info, includes info about our affiliate program.